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NeoMag is the first magneto-mechanical platform that simulates pathological processes in biological systems for more predictive drug testing in a non-invasive, contact-free and portable by design way. Unlike traditional systems that rely on vacuum or direct mechanical stretching to deform membranes, our technology utilizes magnetic fields and smart polymers (MAPs). This allows for the application of precise forces on cells and 3D tissues (organoids) without disturbing the culture media or damaging samples, ensuring a level of biological integrity that was previously impossible to maintain during stimulation. We uniquely solve the lack of predictability in drug development by integrating mechanical realism with ease of use. Our "plug-and-play" platform is compatible with advanced microscopy, enabling researchers to observe in real-time how cells respond to mechanical pathologies, such as cancer or traumatic brain injury. Powered by our AI control engine, scientists can program complex and dynamic deformation patterns, accelerating the discovery of therapeutic targets and drastically reducing the reliance on animal testing.