Aphiotx

AphioTx is a clinical-stage pharmaceutical company developing safe and effective treatments for opioid withdrawal and dependence. The opioid crisis is spreading quickly around the world, with over 29 million people suffering from opioid use disorder. The debilitating symptoms of opioid withdrawal affect all users, not just those who suffer with opioid use disorder. Current interventions to treat opioid withdrawal symptoms rely on long-acting opioid medications that affect normal nervous system function, creating a vicious cycle of treating opioid withdrawal with more opioids. Non-opioid pharmacological options for treating withdrawal are limited, have proven to be largely ineffective, and are known to cause serious side effects. Consequently, less than 30% of patients on opioid replacement therapies achieve abstinence, creating a huge unmet need for millions of people all over the world. Having safe and effective interventions that reduce withdrawal can break the cycle of opioid use.