Arnaud Droit Lab

ADlab focuses on the development of tools dedicated to the analysis of omics-type massive data, including genomics, transcriptomics, proteomics and metabolomics. His work provides a better understanding of the complex biological mechanisms of different diseases or biological phenomena. His team develops various approaches to identify multi-omics signatures using multivariate-driven methods such as machine learning and PLS-DA, and knowledge-based methods such as interaction networks and modules detection. Other projects are focusing on data management of big biological data with interactive graphical layers, to offer a better exploitation of the data. The lab is also involved in medium to large scale collaborative projects with international teams in academics and private sector focusing on breast cancer, prostate cancer, neuro-developmental diseases and pediatrics in order to discover new therapeutics targets. The laboratory expertise is now evolving to the next step, consisting of elaborate strategies to identify drugs of interest by drug repositioning, including drug synergies and secondary effects/toxicity prediction.