Avipero Bio

Avipero Bio is aiming to Transform Cancer Treatment by Stopping Metastasis at Its Source. Avipero Bio’s unique β1-integrin modulators (AVI001, AVI002) inhibit cancer spread and extend survival and are applicable across metastatic The Unmet Need Metastatic Cancer Remains the Deadliest Stage of cancer with 82.6% of metastatic cancer patients dying within 10 months. To date, no drugs effectively prevent or reverse metastasis. There is also rising global incidence with the market expected to be valued at $158B market by The Problem: The Biology of Metastasis Current treatments fail due to multiple factors but mainly due to: • Tumor heterogeneity triggering uncontrolled metastasis. • Integrin overactivation drives invasion and treatment resistance. • Senescence allows metastatic cells to survive and The Solution: AVI001 Avipero Bio’s First-in-Class β1-integrin modulator is unique because it: • Normalizes cell adhesion and restores normal growth signals. • Reverses senescence and blocks metastasis in vivo (60% tumor reduction). • Demonstrated efficacy across multiple solid tumor