Baioflow Inc

About Us Baioflow is an innovative biotech company developing drug delivery vehicles capable of crossing the blood-brain barrier greatest hurdle in CNS drug development. Our core competencies extend beyond conventional software or AI predictions. We integrally execute the entire R&D lifecycle by not only ① discovering novel ligands optimized for neurological disorders, but also ② designing and engineering 'Peptide Shuttles (BPS)' that safely transport therapeutic cargos—such as ASOs, siRNAs, and small molecules—directly into the brain parenchyma. To realize these two core deliverables as tangible therapeutics, we employ an 'R&D Closed-loop System.'[Core Technologies] Target Ligand Discovery & Peptide Shuttle Engineering Through our proprietary platform,'BaioAI NeuroGate™,' we analyze target receptors across 8 specific parameters to identify optimal transcytosis pathways. Simultaneously, we design and validate peptide shuttles engineered to minimize the severe adverse effects (e.g, hypoglycemic shock, anemia) associated with conventional antibodies. Wet-Lab Validation We rigorously test the performance of our discovered ligands and peptide shuttles through comprehensive in vitro and in vivo experiment. BaioTalk™ (AI Optimization): High-quality empirical data generated from our experiments is continuously fed back to retrain 'BaioTalk™,' our bio-domain sLLM (specific Large Language Model). This continuous loop drastically improves the success rates of novel ligand discovery and shuttle development while significantly accelerating the overall R&D timeline. Baioflow seamlessly conducts everything from target discovery to In Vivo validation within a single, unified team. Our goal is to provide a commercially scalable platform capable of delivering our global partners' diverse therapeutics into the brain. Join Baioflow on our journey to establish the new standard in Central Nervous System drug delivery.