Branca Bunus Ltd

Company Overview: Branca Bunús Ltd is an Irish UCD spin-out company developing and commercialising high-performance non-viral gene delivery technologies to accelerate the development and manufacturing of cell and gene therapies. Our flagship technology is a patented HPAE (Hyperbranched Poly(β-amino ester)) transfection platform, engineered to deliver superior transfection efficiency, high lentivirus titres, and excellent scalability compared to conventional reagents (e.g, PEI and lipid-based systems). The platform results in a GMP-ready and cost-effective product, BrPERfect® for virus, which is ideal for large-scale lentivirus vector production. Key Product & Application Focus:> BrPERfect® Transfection Reagent – high-efficiency non-viral vector > Primary application: Lentivirus production in HEK293/293T cells > Compatible with suspension and adherent cell systems > Suitable for serum-free and large-scale bioreactor manufacturing > Enables efficient, cost-effective upstream production for ex vivo CAR-T workflows > Strategic focus: Lentivirus market — currently the strongest validated performance of our technology. Our Strengths:> Proven performance in Asia: validated by multiple biotech and academic partners > High viral titres: demonstrated superior yields compared to conventional reagents > Cost-effective: lower dosage and more affordable than leading commercial reagents > GMP-ready product: scalable for clinical and commercial manufacturing > Excellent stability & simplified process: BrPERfect® forms a stable complex for at least 3 hours at room temperature, providing flexibility in production scheduling; easy to operate with robust performance in large-scale manufacturing.