Famovement

For support of research, we donate proceeds to the internationally renowned Friedreich’s Ataxia Research Alliance (FARA), a national 501(c)(3) non-profit organization dedicated to the pursuit of scientific research leading to treatments and a cure for Friedreich’s Ataxia. Through this mechanism, we rely on the accomplished scientific advisory board of FARA for deciding which research investments are most likely to yield optimal patient outcomes in the most rapid timeframe. The state of research and development in Friedreich’s Ataxia has significantly advanced through the tireless effort of scientists, which have been funded by public grants as well as FARA. Currently, there is an understanding on the molecular basis for the cause of FA and specific mechanisms leading to damage in patients, such as gene mutation, decreased frataxin production, iron-sulfur cluster formation, and mitochondrial dysfunction. FARA is supporting the development of treatments aimed at each of these different mechanisms of damage. Because it is based on solid basic science discovery, this targeted approach to treatment has great potential. Furthermore, FA researchers believe that treatment will come in the form of a “cocktail” therapy - meaning that therapies aimed at the different mechanisms of damage have the potential to be used in conjunction with one another to treat the disorder. More information on the current state of drug development for Friedreich’s Ataxia can be seen on the FARA “pipeline” web page: