Hof Therapeutics

Our platform uses multiple cell types simultaneously to form organ components, whereas other leaders typically use only one, the epithelia. Our breakthrough technology is at the forefront of the field, providing cell assembly programmed (CAP) organs containing the microarchitecture necessary for organ function. Now, in addition to reading RNA levels from the bioassays, you can assess effects on the physiology of the organ - providing new critical endpoints. Following our success in dermatology making full-thickness skin, hair, and sweat glands, we are creating divisions for all major organ systems of the body, which currently includes bone, lung, blood vessels, and cancer / fibrosis models. We aim to become the standard for all pre-clinical studies for drug development based on our suite of superior organ models, providing an assessment of targeted organ effects as well as off-target effects and toxicity. Importantly, our CAP organs also have the potential to revive damaged organs for regenerative medicine applications.