Manifold Bio

Manifold Bio is positioned to be the leading tissue-specific medicines company. We’ve built the first high-throughput in vivo (HTV) discovery engine - combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics. Our engine sculpts pharmacokinetics, biodistribution, and other key properties of biologics directly in living systems, solving previously intractable challenges for tissue-specific delivery. By generating rich, scalable datasets in vivo, Manifold Bio is unlocking AI’s full potential to design targeted, effective therapeutics, and accelerate their path to patients.