Nanofuse Biologics

NanoFuse Biologics LLC, wholly owned by NANISX LLC (a KIC Ventures portfolio company), features NanoFuse® DBM, the first FDA-approved combination of synthetic bioactive ceramic 45S5 bioglass and demineralized bone matrix (DBM) for bone regeneration, promoting fusion and healing. When combined with aqueous body fluid, NanoFuse forms a 3D ultra-porous calcium hydroxyapatite layer within 24 hours, creating a strong bond with adjacent bone. This process triggers osteoblast differentiation, accelerates osteogenesis, and enhances bone growth. Additionally, in vitro studies show ionic release (Ca) and pH changes inherent to bioactive glass create an unfavorable environment for microbes, adding an antimicrobial benefit. Guided by LESS™ Exposure Spine Surgery (LESS) principles and the Restore Function, Early Intervention, and Preserve Anatomy (REP) methodology, NanoFuse Biologics is a trusted bone void filler for fusion and regeneration. With a proven clinical record and patented manufacturing, NanoFuse Biologics LLC delivers a reliable bone regeneration solution.