Physiolution

Physiolution is a an innovative company focused on investigations of the dissolution behaviour of solid oral dosage forms under bio-relevant test conditions. The cutting edge test methods utilized by Physiolution were established by the founders and are based on long experience in the fields of gastro-intestinal tract physiology and biopharmaceutical evaluation of dosage form performance. The bio-relevant test devices realistically simulate the mechanistic and physico-chemical conditions that act on dosage forms during their gastro-intestinal passage and enable the evaluation of their biopharmaceutical safety and reliability. The applicability of the test devices and test procedures was successfully validated on numerous examples of clinical relevance as well as in the routine analyses of solid oral dosage forms. In addition, the analytical services of Physiolution include pharmacopoeial dissolution testing and other pharmacopoeial investigations of solid oral dosage forms and their mechanical stability as well as development and validation of analytical methods and procedures, biochemical characterisation of biomolecules and formulation of peptide drugs. Physiolution was awarded 2016 with the prestigious prize LUDWIG-BÖLKOW-Technologiepreis of Western Pommerania for developing pHysio-grad® and pHysio-stat®.