The Good Clinical Trials Collaborative

The Good Clinical Trials Collaborative, established in 2020, is a not-for-profit organization dedicated to promoting new guidance to enable better randomized controlled trials (RCTs) globally. It is led by Professor Sir Martin Landray, co-Chief Investigator of the Covid-19 RECOVERY trial and supported by Wellcome and the Bill & Melinda Gates Foundation. Guided by the belief that good healthcare is informed by good evidence from good trials, the Collaborative’s objective is to make it easier to do good RCTs with new guidance that sets an international benchmark of scientific rigour, ethical integrity, efficiency and quality. The new guidance was developed through collaboration with a diverse, multidisciplinary group of individuals and organizations with a shared commitment to help accelerate the improvement of healthcare across the world. Outlining the five underpinning principles of good RCTs, the guidance is intended to support all parties involved with RCTs, of all types of health interventions, in all settings. The guidance is available in six languages and can be downloaded from