Biotechnology in Belgium

Pxlence

pxlence (pronounced 'pixel-ence') is a medical technology company developing and manufacturing PCR assays and kits for targeted resequencing or nucleic acid quantification. pxlence was created as a spin-off company from Ghent University in 2015. We identify unmet needs in the detection of patients’ genetic defects and apply innovative solutions. We combine unique expertise in PCR design and multiplex amplification with leading industry knowledge. Using our state-of-the-art high-throughput primer design pipeline, one million PCR assays for targeted resequencing of DNA from fresh frozen or formalin fixed paraffin embedded (FFPE) tissue covering 99% of the human exome were expertly designed. These best-in-class assays enable the enrichment of any exonic region of interest for targeted resequencing (discovery) or for confirmation of variants by means of Sanger or massively parallel sequencing (NGS). The assays are also used for pedigree analysis of variants of unknown significance. More than different assays for 500 disease genes have been successfully tested in diagnostic laboratories (ISO 15189). Using our single-tube multiplex PCR and sequencing library preparation technology, a 50-SNP Human Sample ID Kit was released in 2020, followed by a mini-version covering 13 SNPs in 2022. Most recently, we developed Rainbow DNA detection technology using universal probes for digital PCR and quantitative PCR. Our customers include clinical diagnostic laboratories and medical device companies in the field of PCR based molecular analyses.

1 to 10 staff

Amalus Therapeutics

We convert the power of selective fibroblast modulation into transformative therapeutics. Pathologically activated fibroblasts orchestrate abnormal tissue structure and drive many diseases. Our technology modulates of disease-associated fibroblasts with unprecedented selectivity, resulting in precise tissue remodeling and normalization, and generating multiple therapeutic benefits.

1 to 10 staff

Biomaric Nv

BioMARIC N.V. is a privately owned Belgian biotechnology company founded in August, 2001 predominantly focusing on prevention and control of infectious diseases. BioMARIC continuously maintains global collaboration with the third world scientific and medical community on projects that target to slow down the spread of infectious diseases. VISION Create maximum synergy between different stakeholders to make high quality healthcare products accessible at affordable prices in ALL countries of the world, in particular the growing economy countries and the countries located in resource-poor parts of the world. MISSION Develop next-generation healthcare products to control the spread of infectious diseases and make these products available through decentralized manufacturing in collaboration with local partners CERTIFICATION In 2019, BioMARIC was awarded the EN ISO 13485:2016 certification, which ensures that our products and services meet the stringent quality standards through an effective quality management system. BUSINESS PHILOSOPHY Depending on local market conditions, available know-how and targeted applications, BioMARIC cooperates with its partners to find the best model for cooperation and create maximum synergy to the benefit of all parties involved, including the local community. BioMARIC alliances can be based on several collaborative models: 1. Full Technology Transfer and supply of critical materials for local manufacturing at the partner’s facilities 2. Supply of selected critical detection modules developed for specific use in immunoassays 3. OEM manufacturing of the BioMARIC assay (kit) under the partner’s label

11 to 50 staff

Exo Biologics

EXO Biologics is a Belgian clinical-stage biotechnology company focusing on researching and developing novel sub-cellular therapeutic candidates based on exosomes. Exo Biologics mission is to provide affordable and accessible exosomes therapies to patients with unmet medical needs. Exo Biologics has strong partnerships and influential networks for collaborating and researching new medical treatments, including research centers, public universities, and private partners.

11 to 50 staff

Senior Consultancy Life Science & Technology

Market intelligence studies Venture track preparation Technology valorisation routes Due diligence analysis

1 to 10 staff

Terracottem Bv

TerraCottem. Leading soil conditioning technology that helps you achieve successful planting projects despite the challenging effects of poor soils and climate change. Soil is life. Soil is the skin of the earth. But not all soils are conducive to good plant growth. Many soils need to be amended or conditioned. TerraCottem believes in a holistic approach to plant growth, good horticultural practice and in getting things right from the start. Hence, we produce all-in-one soil conditioners for all types of plants to enhance your work and reduce risk factors. TerraCottem soil conditioners work at the plant’s root level. They are mixed with the soil when planting. Each TerraCottem soil conditioner contains nutritive, growth stimulating and water absorbing components. They all work in synergy to stimulate root development and plant growth, even in poor and degraded soils. TerraCottem provides a constant supply of water and nutrients around the root system reducing drought stress and plant mortality. It has a dual effect: you get sustainable, healthy plant growth and savings of up to 50% in irrigation water, even in challenging conditions. It also reduces nutrient leaching. TerraCottem makes greenery thrive with less inputs. A win-win situation for you, your clients and the environment. At TerraCottem we are committed to help you create more fertile soil. Nature just got better.

1 to 10 staff

Wakati Bvba

Affordable and clean technology for extending the shelf life of fruits and vegetables in developing counties. Smallholder farmers are the backbone of the economy in developing countries, of which woman carry more than their share. Their success or failure means the difference between eating and NOT eating for over 870 million people who are food insecure around the world. Smallholder farmers face an unsustainably high percentage of losses each and every year. According to the FAO, 45% of fruits and vegetables in developing countries never reach the consumer. That’s 45% less food in markets, on tables and in mouths. This postharvest loss is a result of smallholder farmers lacking adequate protection for their produce from the climate, pests and diseases. Nearly half of their investment of time and resources is needlessly wasted, resulting in higher prices for the entire population. “Improving the productivity, profitability, and sustainability of smallholder farming is the main pathway out of poverty in using agriculture for development.” Kofi Annan Reducing post-harvest losses is the most effective and sustainable solution to hunger and food insecurity. Wakati is a simple and innovative solution that alters the climate of fruit and vegetable storage spaces to increase shelf life and reduce post-harvest losses by over 20 percent. The climate control approach used by Wakati is a affordable and clean-technology. This life changing alternative increase the income by providing better quality and more crops by lowering the losses while the extended shelf live provides more time for growing crops, getting them on the marketplace and a better bargaining position to the local wholesalers.

1 to 10 staff

Alfaplant Bvba

Alfaplant BVBA was founded in 2005 when this subsidiary was split off from Raf Goossens BVBA as a result of their growth of in vitro propagation activities. We mainly focus on Rhododendrons, Azalea’s, Vacciniums, etc. for our own production but we are continiously looking for new partnerships and new varieties to grow in vitro. Ask us for more information – info@rafgoossens.be

1 to 10 staff

Tnrr Lab

Re-wiring nuclear receptor-based action for enhanced therapeutic benefit.

11 to 50 staff

Forlab N.V

ForLab is a reliable Belgian company specialized in the import and distribution of diagnostic and life science reagents from worldwide suppliers into Belgium, The Netherlands and Luxembourg. The company was founded in 1982 and the headquarter is based in Brussels. Our customers are located in laboratories of academic and general hospitals, universities, veterinary institutes, governmental laboratories, contract research organizations, pharmaceutical and biotech companies. Our goal is to offer an extensive and complete range of high quality products for all their laboratory needs, varying from ELISA kits,(q)PCR, inhibitors, recombinant proteins and rapid tests.

1 to 10 staff

Railroad Therapeutics

We are a Belgian company dedicated to the discovery of novel cancer medicines. We apply state-of-the-art novel technology to treat patients with solid tumors.

1 to 10 staff

Harmony Clinical Research Bv

11 to 50 staff

Spin Healthcare

1 to 10 staff