Directory · IL
Biotechnology in Israel
A register of firms and the professionals working at them in the Biotechnology sector based in Israel. Browse the public index, then filter or export on Kipplo.
Companies
89 on file
Grace Breeding
Grace Breeding is an agro-tech company focused on developing efficient and sustainable, nitrogenous, bio stimulant and climate stress relief products for farmers and agricultural-product distributors. Grace Breeding aims to address some of the most significant challenges facing the agriculture industry with natural, sustainable, and environmentally sensitive solutions. With climate change putting an increasing amount of stress on the $8T global agricultural industry, Grace Breeding is bringing to market products that remove carbon from the agricultural supply chain while improving crop economics – specifically through improving yields and crop health, and by boosting the overall resilience of fruits, grains, and legumes alike. Grace Breeding’s mission is dual: to improve crop health and provide bio stimulant and climate stress relief solutions that support farmers as well as to provide sustainable agricultural solutions for the Earth. Grace Breeding is developing products that can improve a plant’s ability to adapt to climate change, while at the same time, reduce GHG emissions that are a persistent by product of conventional solutions that typically contain urea. The Company’s core products (Nitrogenous Technology “NFT” and Wide Defense System “WDS”) leverage the power of biological-based compounds and naturally occurring bacteria to improve crop yields and enhance plant resiliency. Grace Breeding’s solutions help a broad range of high-value crops to withstand the effects of droughts as well as environmental threats that are prevalent yet often unpredictable. Furthermore, NFT reduces reliance on urea and therefore farmers’ exposure to the price volatility which was caused by the Russia’s invasion of Ukraine and resulting lack of raw materials supply from Russia. Grace Breeding was founded in 2015 and is headquartered in Rehovot’s science park with an R&D center in Jazreel valley, Israel.
1 to 10 staff
Hadassa Medical Centers The Hebrew University Jerusalem
Dental Medical Devices, Oral Medicine Devices Phototoxic Effect of Non-Coherent Light on Perio-pathogens Our device for treating microbial diseases in local infections comprises the step of emitting a blue light beam towards the tissue to be treated without warming the tissue so that a selective or non-selective phototoxic effect is exerted inter alia by regulating various levels of parameters selected from blue light. Periodontitis is prevented by inhibiting predetermined bacterial lawn from growing into biofilm. This phenomenon could be enhanced in the presence of chemical cofactors such as oxygen precursors for ROS production. A Method & Device for Teeth Whitening Our invention answers an urgent need for a cost effective bleaching agent containing whitening material which is adapted for homely time-saving use. Moreover, it provides a stable, conveniently applicable product that is adapted to prevent chemical swallowing effects as well as contact with soft body tissues and teeth erosion while possessing hardening abilities during the treatment process. A Method & Device for Teeth Whitening Our invention answers an urgent need for a cost effective bleaching agent containing whitening material which is adapted for homely time-saving use. Moreover, it provides a stable, conveniently applicable product that is adapted to prevent chemical swallowing effects as well as contact with soft body tissues and teeth erosion while possessing hardening abilities during the treatment process.
5001 to 10000 staff
Interna Therapeutics
Interna Therapeutics is an innovative biotechnology company that developed a transformational delivery technology for macromolecules. The pioneering technology, named Molecular Nano-Motors (MNMs), is based on a novel mechanism that leverages membrane electrical forces, facilitating entry of charged molecules into cells. With this technology new treatment options become available for a wide range of diseases using difficult to deliver molecules such as oligonucleotide-based drugs (siRNA, ASO). Equipped with full-capacity research facilities and working with leading research organizations, the team of seasoned scientists has demonstrated the therapeutic potential of MNM technology in numerous preclinical studies, with a Phase I study of a COVID-19 drug that began in September 2024. Interna’s innovative spirit and scientific excellence has been recognized by key opinion leaders in the pharma industry and by non-governmental organizations.
11 to 50 staff
Lempo Therapeutics Ltd
We are a pre-clinical biotech company, pioneering a paradigm shift in the modification of the innate immune system to effectively combat severe diseases. Our patented novel treatment uses ex-vivo stem cells gene-editing technique to minimize the collateral damage caused by the immune system as a result of its activity. By doing so, we expect to attenuate the progression of these diseases significantly. We focus first on treating Pulmonary Arterial Hypertension (PAH), a rare, devastating cardiovascular disease which, if left untreated, leads to heart failure and death. There is currently no cure for this disease, and the primary aims of the current treatments are to improve symptoms and increase exercise tolerance. Our concept has already been proven to work in animal models of Alzheimer's Disease, Multiple Sclerosis, cardiovascular diseases, and more.
1 to 10 staff
Nasvax
NasVax develops improved vaccines and immunotherapeutic products. The company has four distinct product areas: i. oral anti-CD3 monoclonal antibody immunotherapeutic; ii. VaxiSome® technology, which is an adjuvant-delivery system for enhancing the immunogenicity of vaccines and immunotherapeutics; group-common pneumococcal vaccine, which is a protein-based vaccine that could become the field’s third-generation product; and iv. BBS1-based immunotherapeutics for Alzheimer’s disease.
11 to 50 staff
Nutrinia
NUTRINIA IS A NEONATOLOGY FOCUSED COMPANY THAT TREATS RARE CONDITIONS OF THE GASTROINTESTINAL TRACT. Nutrinia is developing pharmaceuticals to treat rare conditions of the gastrointestinal tract. Our current products in development are oral formulations of insulin shown to enhance adaptation and rehabilitation of the gut in infants. We at Nutrinia live by the belief that science is best used to make life better for people, especially the most vulnerable populations.
11 to 50 staff
Algalo Industries Ltd
ALGALO Industries ltd - an innovative algae growing technologies. Specializing in designing low cost photo bio-reactors and growing micro-algae. Our Head quarters located in the north of Israel, where we develop the next generation of our bio-reactors.
1 to 10 staff
Climatecrop Ltd
With our cutting-edge technology, we can produce more with less land, water, and chemicals, thanks to a discovery of the gene that controls how much daily starch is stored in leaves. We also found that the increased starch allows plants to withstand extreme conditions and thrive during them too! For example, when it comes to droughts or heatwaves - which are common nowadays due to their high frequency-our crops have been shown increase yield compared to other counterparts without any genetic alterations.
1 to 10 staff
Metabomed Ltd
Metabomed is a drug discovery company in the field of cancer metabolism. The Company is developing a proprietary target identification platform based on computational biology, genomics and metabolomics. The platform identifies metabolic pathways that arise uniquely in cancers that enable and support their growth. These discoveries are used to develop small molecules that specifically target the reprogrammed cancer cells’ metabolism to halt their growth. Since these molecules inhibit divergent pathways that are specific to cancer cells, the therapies will not target healthy surrounding tissues. Metabomed is a privately held company based in Israel and supported by the groundbreaking science of its scientific founders.
1 to 10 staff
Prevera
Prevera Food Protection Proteins - Transforming Food Safety from a Liability to an Asset. Access to safe and healthy food & beverage is a key element of our well-being. However, when it comes to food safety, the food industry faces major challenges. Most food products contain unhealthy preservatives, while others rely on ineffective methods that shorten shelf-life and increase spoilage levels. Our mission is to provide safe and healthy food by utilizing Food Protection Proteins, which eliminate the need for harmful preservatives and reduce food waste. Our cutting-edge food & beverage protection solution is based on an antimicrobial short protein – nature’s weapon against pathogens. • Highly effective, replaces harmful preservatives • Safe for consumers and the environment • Unaffecting our microbiome • Extends product shelf-life, reduces food waste
1 to 10 staff
Prospec Tany Technogene Ltd
ProSpec (Protein-Specialists) is a leading biotechnology company having over 20 years of experience specializing in production of prokaryotic and eukaryotic-derived recombinant proteins. The company provides highly purified proteins worldwide which serve the life science research community with cytokine-related products. Our goal is supplying many recombinant proteins which serve the academic and R&D industry. We have been able to assemble more than recombinant proteins, peptides and antibodies which are crucial to the research community.
11 to 50 staff
Aporx
ApoRx is a drug discovery company focusing on the discovery, design, characterization, and development of small proteolysis targeting molecules (PTMs) against well-validated disease-causing proteins in cancer and other indications. Our technology is based on a proprietary focus library of RING E3 ligase binders and is designed to harness the intracellular Ubiquitin-Proteasome machinery to degrade and destroy unwanted proteins by Targeted Protein Degradation.
1 to 10 staff
Citrine Solutions Ltd
CITRINE Solutions Ltd. is a boutique consulting firm with extensive experience and a proven record of accomplishment in advisory services for the following fields: 1. Digital Health - Technology assessment, design and integration for digital products 2. Life Science & Diagnostic Laboratories – Establishing laboratories (COVID-19, cannabis, biotech) We bring our in-depth knowledge to assist in improving the business model, identifying and managing risks, developing methodologies, shortening bureaucratic processes and reducing uncertainty in competitive fields. Citrine Solutions specializes in analyzing and closing the gaps between the health organization's requirements and the limitations of the products in the development stages. Our professional services will guide you throughout the project life cycle. We consult for top level laboratories, identifying optimal locations and imparting the highest safety and GLP standards. Among our clients We have been privileged to work closely with top ranking laboratories, incubators and startups, health care organizations, hospitals, biotech companies, R&D initiatives and government organizations. Our clients include entrepreneurs, CEOs, lab managers and researchers. Featured projects Israeli Ministry of Health (MOH), Challenge Program Assisting 14 startup companies and health care organizations to define and implement digital healthcare solutions, including face recognition, drug interaction monitoring, elderly monitoring and fall prevention, hybrid medicine, and care giver management. Maccabi Healthcare Services, DAPHNE Project, EU's Horizon 2020 program. Collaborating to design mobile application that collects data from wearable sensors and integrates it into Electronic Medical Records (EMR), using analysis pipelines, high-performance computing (HPC), and machine learning (ML) technologies. Aid Genomic Consulting to the CEO for the design and construction of private COVID-19 laboratory
1 to 10 staff
Epeius Pharma
Epeius pharma is a cell and gene therapy company developing next-generation biological vehicles for delivery of therapeutic proteins into the central nervous system (CNS). Efficient and predictable therapeutics delivery is particularly challenging in neurological diseases due to the blood-brain barrier which tightly regulates the transport of molecules to the brain, and blocks the transport of most large, charged and hydrophilic molecules, which are common features of therapeutic agents. The lack of efficient CNS delivery methods limits protein replacement therapy and remains to be one of the greatest unmet needs for neurological disorders treatment. While the problems of delivery across the and into cells present crippling challenges for drug delivery, some organisms have independently evolved to breach the and secrete proteins to their host’s cells. A striking example is Toxoplasma gondii, a highly prevalent intracellular protozoan parasite, which infects all warm-blooded organisms. It is estimated that 30% of human population have antibodies for Toxoplasma gondii, which indicates they were exposed for Toxoplasma in their life span. Upon entry into the human body, T. gondii actively migrates to the brain and passes the blood brain barrier Most importantly, throughout the infection, T. gondii secrets effector proteins into the host neuron cells and into the extracellular brain environment.
1 to 10 staff
Gaia Bio
A first Synthetic Biology platform focused on environment and sustainability
1 to 10 staff
Lipogen
Developing and manufacturing phospholipids since 1991. Being the first to globally introduce and clinically test soy Lecithin Phosphatidylserine (PS), the only dietary ingredient with FDA qualified health claims for cognitive dysfunction and dementia in the elderly. Safe, effective, unique and affordable. Focused on delivering high quality products at a competitive price, after extensive clinical research and complete patent protection, Lipogen offers specialty phospholipids for stress management (Lipogen PSPA™) and cognitive function support (Memree™), enhancing well-being and improving quality of life.
11 to 50 staff
Reagenics
Reagenics (Research Ltd.) is a plant molecular harvesting company specializing in the production of molecular compounds grown in bioreactors. Reagenics' innovative technology platform, rooted in cell tissue culturing, aims to become a market leader for a range of pharmaceutical, medical and wellness products.
11 to 50 staff
Rnable
RNAble is a preclinical biotechnology company developing a potent small-molecule inhibitor targeting FTO, a key driver of oncogenic RNA biology. Mechanistic studies have led to the identification of a specific biomarker that predicts pan-cancer sensitivity to the inhibitor across both hematological and solid malignancies. Key highlights of RNAble's lead candidate: • Demonstrates strong in vivo efficacy and superior antitumor activity compared to standard-of-care therapies in AML models. • Shows promising efficacy in preclinical models of biomarker-selected solid tumors. • Features a novel, validated mechanism of action that induces cancer cell death via RNA-mediated mitotic catastrophe followed by apoptosis, with potential to overcome resistance to current therapies. • Exhibits strong oral bioavailability and a favorable safety profile. • Expected IND submission in 2026.
1 to 10 staff
Croptimal Ltd
Croptimal is offering a unique service for performing real-time and accurate tests of crops, soil and water in the field. This novel and innovative technological solution reduce time-to-analysis from 10 days to 10 minutes, dramatically changing the prevailing agricultural testing methodology.
11 to 50 staff
Vivox - Experts In Vivo
Vivox, experts in vivo, is one of the leading CROs in Israel, aiming to become one of the top CROs worldwide and a leading player in developing the Israeli ecosystem of the biotech industry. Our passion and specialty are supporting pharmaceutical-oriented companies in their preclinical research stages. We provide end-to-end solutions of professional preclinical services designed and performed by our team of experts, both in vivo and in vitro. As a young, dynamic, Customer-oriented, and agile company, we work tirelessly to ensure optimal results for each experiment we conduct as accurately and quickly as possible. We are honored to share our preclinical services and knowledge with our clients to advance potential new therapies towards clinical stages and beyond. We work according to established models of Metabolic Diseases, Degenerative Diseases, Immunological Models, Oncological Models, and General Models. In addition, we offer special surgical expertise, analytics, cell culture, and ex vivo studies services. Vivox is dedicated to support and promote medical oriented companies to cross their pre-clinical stages for successful FDA, IND application, we are honored to share our pre-clinical services and knowledge both in-vivo and in-vitro with our clients in order to advance potential new therapies towards clinical stages and beyond.
11 to 50 staff
Nexthen
NextHen is led by industry experts and operates based on a joint venture with the Agriculture Research Organization (ARO)- the Ministry of Agriculture of the State of Israel. NextHen specializes in identification through to expression of advantageous phenotypes (traits) of both broilers and layers in the poultry industry. Its flagship project is providing a sustainable, cost-saving way to end the culling of male chicks, by enabling the laying of eggs from which only non-GMO females hatch - the only viable method to end the slaughter of 7 billion chicks each year. Breeders can now benefit from an increase in production volume and efficiency by freeing up significant incubation space, without any changes to the manufacturing process or additional machinery; Significant cost reduction related to the egg sorting process (human and machine); And accelerate production process by reducing the volume of eggs transferred into incubators.
11 to 50 staff
Spivak Cro Services
Bio-medical research, Pre-clinical & In-vivo models establishing; Pharmacokinetics & Pharmacodynamics; Toxicological and Efficacy services. Development of novel drugs candidate with a focusing on CNS, Oncology, Urology, Dermatology, Cardiology, Pulmonology and Inflammatory. Respiratory, Ophthalmic, Urological, Neurological and Metabolic diseases; Clear understanding of IACUC; Establishment of high-quality feasibility studies. • Various CNS & Ophthalmic microsurgery techniques & models: Middle Cerebral Artery permanent/ temporary occlusion; Brain implantation techniques; Traumatic Spinal Cord Injury; Optic Nerve Axotomy; Episcleral vein occlusion, Retinal Ischemia Reperfusion, and Retrograde RGC labeling. • Abdominal surgery techniques & metabolic models: Unilateral Ureter Obstruction; 5/6 Nephrectomy; Acute Renal Failure; Chronic Renal Failure; Unilateral Nephrectomy/Renal Ischemia Reperfusion; Bile Duct Ligation; Micro osmotic pump implantation. • Micro injections techniques: Intranasal; Intratracheal; Intravitreal; Retro-orbital sinus; Retro-bulbar; Sub Conjunctival; Portal Vein; Brain Intraventricular; Intrathecal; Hydrodynamic high-pressure. • Rodent cancer models: for screening tests of new small molecule/drug discovery projects, tumor cells implantations; metastatic/host tumor models. • Research experience in small animal dissections & sampling procedures: blood vessel cannulation; intra cardiac/tracheal/portal vein perfusion; blood collection, tissues micro dissection & harvesting, organs sampling preparations for complete histology, molecular and other analyses • Research efforts and physiological/behavioral monitoring systems application; invasive and non-invasive monitoring techniques • Digital image preparation and analysis.
1 to 10 staff
Merkel Technologies Ltd
Give Your Research The Chance It Deserves! We provide advanced technologies, instrumentation and reagents that assist researchers in achieving exceptional results. We're passionate about helping researchers and companies obtain substantial results - by providing them with unique and advanced technologies that release their R&D bottlenecks and enable them to reach their milestones earlier. Our main areas of specialization are: flow cytometry, flow imaging, cell sorting, nanoparticle analysis, and many pre-clinical imaging modalities, including: micro-CT, bioluminescence/fluorescence imaging, optoacoustic imaging, fiber-based confocal in-vivo imaging, 2D X-Ray, ultrasound. We also offer various solutions for plant and material sciences.
1 to 10 staff
Polyrizon Ltd
We are a development stage biotech company specializing in the development of innovative medical device hydrogels delivered in the form of nasal sprays, which form a thin hydrogel-based shield containment barrier in the nasal cavity that can provide a barrier against viruses and allergens from contacting the nasal epithelial tissue. Our proprietary Capture and Contain TM, or C&C, hydrogel technology, comprised of a mixture of naturally occurring building blocks, is delivered in the form of nasal sprays, and potentially functions as a “biological mask” with a thin shield containment barrier in the nasal cavity. We are further developing certain aspects of our C&C hydrogel technology such as the bioadhesion and prolonged retention at the nasal deposition site for intranasal delivery of drugs. We refer to our additional technology, which is in an earlier stage of pre-clinical development, that is focused on nasal delivery of active pharmaceutical ingredients, or APIs, as Trap and Target ™, or T&T.
1 to 10 staff
