Aidan Smith

Background

About Aidan Smith

PhD neuroscientist with 12+ years identifying and targeting therapeutic targets and mechanisms for neurodegenerative and inflammatory diseases. Extensive hands-on and managerial experience in developing platform technologies, devising and executing drug discovery and pharmacology investigations in preclinical models resulting in high-impact publications and funding. In-depth experience in animal disease modeling, PoC studies, delivery across target identification and validation, efficacy, and safety studies. Proficient in approaches of investigating the pathobiology of CNS and systemic diseases and evaluating the response to potential therapeutics in cell and animal models at the levels of ()(learning and memory, anxiety, pain, cognition, motor function, and socialization),()(histology, IHC, IF and state of art image quantitative methodologies)()(primary and established cell lines in culture, cellular efficacy assays, fluorescence microscopy, gene KD/KO, and, viral vectors),()(transcriptomics, proteomics, epigenomics) and ()(gene, protein and metabolite based markers in brain, relevant organs and biofluids). Strong written and communication skills with a detail-oriented mindset, analytical and problem-solving skills as evidenced by 12 publications in high impact journals and 20+ oral/poster presentations Outstanding multitasking, collaborative team builder, leadership skills, proven ability to maintain timelines with flexible workloads. Played a pivotal role in developing cross-functional therapeutic programs across 6 genetic diseases. Successfully trained, supervised, and mentored 30 young researchers (Postdocs, Graduate/Undergraduate students, research technicians)