Anil Repale

Background

About Anil Repale

Synthetic chemist with extensive experience in the pharmaceutical industry focusing on traditional medicinal chemistry synthesis and an extensive knowledge of parallel synthesis To manage all chemistry activities like literature search, route selection, process development, scale up activities in assigned projects ensuring the delivery within competitive timeframes * Proven ability to prepare focused libraries/compounds under strict timelines.* Skilled in the use of microwave. Specialties Small Molecule Libraries, Combinatorial Chemistry, Multi-Step Organic Synthesis, Parallel Synthesis, Microwave Chemistry. Development of APIs in the laboratory. This involves literature survey and proposal of new scheme for exisisting drug.Route selection, development of Non Infringing process and synthesis of bulk drugs conforming to quality specified by IP, BP, and USP. Process optimization & laboratory scale up, Cost reduction. Polymorphic study of API, preparation and Isolation of Impurities. Purification by recrystalisation. Scaling-up of API from laboratory scale to the pilot plant and technology transfer up to plant for commercial production. Quality analysis of APIs and there intermediates, result interpretation as GC, HPLC, IR, NMR, MASS and other routine analytical analysis. Having knowledge of preparation of Documents such as Technical Transfer Document (TTD), Drug History Report (DHR), and Costing of API.