Chenyu Lin
Senior Scientist at Biolexis Therapeutics, Inc
Based in Columbus, United States
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Seniority
Staff
Department
Research & Development
Location
Columbus
Industry
Biotechnology Research
Company size
16
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c•••••••@biolexistx.com
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Background
About Chenyu Lin
Skills co-immunoprecipitation (co-IP) assay, RNA Immunoprecipitation (RIP)/ DNA-RNA immunoprecipitation (DRIP) assay, ChIP assay, UV cross-linking and immunoprecipitation (CLIP) assay, CRISPR Knockout and CRISPR dropout screen, RNA secondary structure assays: including global-scale mapping of RNA-RNA duplexes crosslinked in vivo based on ‘‘Ligation of interacting RNA followed by high-throughput sequencing’’ (LIGR-seq) and DMS-seq, ribosome profiling assays, RNA decay assay, global identification of RNA–protein interactions using orthogonal organic phase separation assay, RNA-seq data analysis based on Galaxy and R language, xenograft assays, in vivo image assays, primary neuron cell purification and culture. Work History Postdoctoral Researcher, 02/2018 to now The Ohio State University-Columbus, OH The global mapping of RNA-interactome in AML patient samples and identify novel functional RNA binding proteins Identification RNA binding sites of RBPs via CLIP and PARCLIP assays Global mapping of human RNA-RNA inter and intramolecular interaction via LIGR-seq Detect how RBP affect translation efficiency via ribosome profiling and RNA-seq Investigate the mechanism of R-loop formation and DNA damage response via DRIP Honors 2012 National Scholarship, Anhui University of Chinese Medicine 2014 Best scientific presentation, Pharmacology Symposium 2016 National Scholarship, China Pharmaceutical University 2017 Excellent Doctoral Dissertation Scholarship, China Pharmaceutical University 2019 Pelotonia Postdoctoral Fellowship, The Ohio State University, United States Complete List of Published Work in My google scholar: https://scholar.google.com/citations?hl=en &
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