Chris Lamb

Background

About Chris Lamb

I lead a translational gastroenterology research group within the Faculty of Medical Sciences and am a Consultant Gastroenterologist at the Newcastle Hospitals with a specialist interest in Inflammatory Bowel Disease (IBD; encompassing Crohn’s disease and ulcerative colitis). I lead an integrated research programme in IBD precision medicine spanning the translational spectrum from mucosal immunology and microbiology, to clinical trials, health economics and clinical quality improvement. My laboratory group investigate the intestinal immune system, how this maintains health or can drive inflammation, and how our immune system interacts with, and is shaped by gut microbiota (bacteria, viruses and fungi) and diet. Having previously undertaken a Wellcome Trust Clinical Fellowship in Translational Medicine and Therapeutics, I have worked within and continue to collaborate with the international biotechnology sector to best translate laboratory findings into patient benefit. I am the Chief Investigator for the national IBD-RESPONSE and CD-metaRESPONSE studies: Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis, funded by the Medical Research Council and The Helmsley Charitable Trust. This programme aims to develop a predictive model of response to immune modifying therapy in IBD based on human immune, gut microbiome, metabolomic and dietary data. I am Clinical Chief Investigator for Open-IBD: Longitudinal multi-omics inception study of Crohn's disease and ulcerative colitis, funded by Open Targets and the Wellcome Sanger Institute. I am also Deputy IBD lead for the EU funded programme, IDEA-FAST: Identifying Digital Endpoints to Assess Fatigue, Sleep and activities of daily living in neurodegenerative disorders and immune-mediated inflammatory diseases. In 2023, I was awarded the Sir Francis Avery Jones medal for research excellence from the British Society of Gastroenterology and have been a previous recipient of the President's medal for outstanding contribution to the Society. In 2023 I was awarded a Rising Star by United European Gastroenterology. & hl=en