Daisy Sarma

Background

About Daisy Sarma

An interdisciplinary chemist with expertise in the design and development of synthesis pathways in the areas of organic, material, and nucleic acid chemistry. Demonstrated ability to work independently to design experiment and troubleshooting. Working in a cross-disciplinary environment, a strong team player with a track record of achievements in scientific publishing and communication. With a passion for drug discovery, seeking a new, challenging position that will allow me to use my strong scientific background in professional environment. Expertise in small organic molecules, modified nucleoside, nucleoside triphosphate, phosphoramidite synthesis and skilled in solid phase synthesis of modified oligo-nucleotides (DNA, TNA and SNA) using ABI 3400 DNA synthesizer and oligo purification through prep HPLC, denaturing PAGE gel. Key Technologies and Methodologies:* Mill-Gram Scale/Multi-step synthesis.* Inert atmosphere and moisture sensitive synthesis.* Purification: Column Chromatography, Automated flash chromatography, Preparative TLC, Lyophilization, Recrystallization and prep HPLC. Analytical Techniques: HPLC, NMR(1D and 2D), MALDI-TOF, ESI-MS, UV-Vis, Fluorescence, FTIR GC-MS, PXRD, XPS,Raman, SEM & TEM. Scientific database tools: Scifinder & Reaxys. Chemistry Software: MestroNova, Topspin, OriginPro, Chemdraw.