David Sibrac

Chargé De Recherche at Pierre Fabre Laboratories

Based in Toulouse, France

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Seniority

Staff

Department

Research & Development

Location

Toulouse

Industry

Pharmaceutical Manufacturing

Company size

9.5K

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Email

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d•••••••@pierre-fabre.com

Phone

5 credits

+33 ••• •••• ••••

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Background

About David Sibrac

Publications: 1. Virtual screening on an α-helix to β-strand switchable region of the FGFR2 extracellular domain revealed positive and negative modulators. Proteins. 2014 Nov;82(11):2982-97. doi: 10.1002/prot.24657. Epub 2014 Aug 30. Automated image analysis of in vitro angiogenesis assay. J Lab Autom. 2013 Oct;18(5):411-5. doi: 10.1177/2211068213495204. Epub 2013 Jun 28. Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling. Cancer Cell. 2013 Apr 15;23(4):489-501. doi: 10.1016/j.ccr.2013.02.018. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23(4):477-88. doi: 10.1016/j.ccr.2013.02.019. Human alpha 2A-adrenergic receptor gene expressed in transgenic mouse adipose tissue under the control of its regulatory elements. J Mol Endocrinol. 2002 Oct;29(2):251-64. Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis. J Lipid Res. 2002 Jun;43(6):904-10. Expression of ectolipid phosphate phosphohydrolases in 3T3F442A preadipocytes and adipocytes. Involvement in the control of lysophosphatidic acid production. J Biol Chem. 2002 Jun 28;277(26):23131-6. Epub 2002 Apr 15. Development of nutritional obesity in transgenic mice with an adrenergic receptivity in adipose tissue comparable with that of humans. Pathol Biol (Paris). 2002 Feb;50(1):52-7. French.

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