Frederick Goulette
Director of Research and Development at Lang Pharma Nutrition
Based in Coventry, United States
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Seniority
Director
Department
Research & Development
Location
Coventry
Industry
Health; Wellness and Fitness
Company size
57
Contact information
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f•••••••@langpni.com
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Background
About Frederick Goulette
Publications: prior to 1994 omitted. Abstracts omitted. Darnowski JW, Goulette FA, Guan YJ, Chattered D, Yang ZF, Cousins LP, Chin YE. Stat3 cleavage by caspases: impact on full-length Stat3 expression, fragment formation, and transcriptional activity. J Biol. Chem. 2006 Jun 30; 281(26):17707-17. Cousins LP, Goulette FA, Darnowski JW. JAK-mediated signaling inhibits Fas ligand-induced apoptosis independent of de novo protein synthesis. J Immunol. 2005 Jan 1; 174(1):320-7. Darnowski JW, Goulette FA, Cousens LP, Chatterjee D, Calabresi P. Mechanistic and antineoplastic evaluation of taurolidine in the DU145 model of human prostate cancer. Cancer Chemotherapy Pharmacology 2004 Sep 54(3):249-58. Allegrini G, Goulette FA, Darnowski JW, Calabresi P. Thrombospondin-1 plus irinotecan: a novel antiangiogenic-chemotherapeutic combination that inhibits the growth of advanced human colon tumor engrafts in mice. Cancer Chemotherapy Pharmacology. 2004 Mar. Ribizzi I, Darnowski JW, Goulette FA, Akhtar MS, Chatterjee D, Calabresi P. Taurolidine: preclinical evaluation of a novel, highly selective, agent for bone marrow purging. Bone Marrow Transplant. 2002 Feb. Calabresi P, Goulette FA, Darnowski JW. Taurolidine: cytotoxic and mechanistic evaluation of a novel antineoplastic agent. Cancer Res. 2001 Sep 15; 61(18):6816-21. Ribizzi I, Darnowski JW, Goulette FA, Sertoli MR, Calabresi P. Amifostine cytotoxicity and induction of apoptosis in a human myelodysplastic cell line. Leuk Res. Jun;24(6):519-25. Davol PA, Goulette FA, Frackelton AR Jr, Darnowski JW. Modulation of p53 expression by human recombinant interferon-alpha2a correlates with abrogation of cisplatin resistance in a human melanoma cell line. Cancer Res. 1996 Jun 1;56(11):2522-6. Darnowski JW, Goulette FA. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8. Biochem. Pharmacol. 1994 Nov 1;48(9):1797-805.
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