Henry Clemente
CEO at Clemente Associates Llc
Based in Madison, United States
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Seniority
C-Team
Department
General Business & Management
Location
Madison
Industry
Nanotechnology Research
Company size
6
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h•••••••@clemente-associates.com
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Background
About Henry Clemente
We have been working for several years with various animal and human studies to determine how to improve fertility rates. Regarding human studies approximately 100 semen purification and IVF treatments have occurred by a 3rd party IVF clinic in the USA with a 75% fertility rate. By so doing we avoid subsequent IVF preparations and costs.The technology involves using our proprietary magnetic Nano particle NP technology that either depletes apoptotic sperm and acrosome reacted sperm or enriches for Mitochondrial Membrane Potential MMP. These Nano particles are added after density gradient Centrifugation DGC. The particles are then targeted to specific sperm membrane sites [apoptotic and acrosome reacted, deficient MMP] and then depleted with a laboratory magnet. This is a negative depletion so no magnetic Nano particles remain and the targeted sperm is enriched. Remember DNA damaged sperm may still be motile], Total elapsed time for the magnetic particle treatment and removal of all magnetic particles is 45 minutes. Studies have been conducted demonstrating damaged DNA in sperm is depleted with this technology The following web site has contain the interview with the IVF physician. http://fox2now.com/2016/01/05/sperm-selection-increasing-chances-of-procreation/ Some of the NP that are targeted and available for purchase are. Apoptosis targets Externalization of phosphatidylserine SUMO [small ubiquitin DNA Defragmentation Lectins bio markers for clinical diagnosis of sub fertility ABA, MPL, PNA, PSA The 3 particles, lectin, apoptosis and Defrag are used all at once to target 3 sperm sites Three different labs have confirmed that washed sperm Vs. Density Gradient has good motility from 25% to particle treated sperm 80%. DNA fragmentation has been reduced 70-90% DGC prepared sperm have had motility increases from 80% to 95% after treatment with the removable magnetic particles Henry clemasso@gmail.com
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