Jason Pontrello
Visiting Research Scholar at University Of Michigan
Based in Boston, United States
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Seniority
Staff
Department
Research & Development
Location
Boston
Industry
Higher Education
Company size
38K
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j•••••••@••••••.com
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Background
About Jason Pontrello
Recent Experience with Blueprint Medicines: Simultaneous project planning for multiple different programs, data collection, and data analysis to elucidate structure and identification of API synthetic route compounds and novel impurities formed in synthesis of drug substance or drug product. Direct projects and manage data collection both through CRO and CMO vendors as well as internally. Authorship of sections for IND submissions and thousands of pages of internal characterization and other reports for compounds and related impurities. Determine compound structure by analysis and review of data including 1D and 2D nuclear magnetic resonance spectroscopy (NMR), mass spectrometry (MS), infrared spectroscopy (IR), UV-Visible spectroscopy (UV-Vis), and single crystal X-ray structure for regulatory starting materials (RSM), intermediates, active pharmaceutical ingredients (API), and associated impurities. Collaboration across Analytical Development, Process Chemistry, and Discovery departments to identify synthetic products and optimize reaction strategies. Data Integrity Review of sections for NDA and IND submissions.
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