Marcus Ohara
Senior Research Associate at Biontech Se
Based in Boston, United States
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Seniority
Staff
Department
Research & Development
Location
Boston
Industry
Biotechnology Research
Company size
5.2K
Contact information
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m•••••••@biontech.com
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Background
About Marcus Ohara
Senior Research Associate with expertise in oncology and immuno-oncology drug development across antibody-drug conjugates and small molecule programs. Skilled in early target discovery, CDR validation, and bioinformatics-to-bench translation using advanced sequencing and assay platforms. Proficient in flow cytometry, spectral panel design, and T-cell functional assays for biomarker expression and immune activity profiling for infectious disease vaccine development. Experienced in next-generation sequencing, single-cell multi-omic library preparation, and transcriptomic analysis using 10X Genomics and Illumina platforms. Experienced in implementing and troubleshooting automation techniques for sample processing and NGS library preparation Experienced in molecular biology techniques including PCR, qPCR, siRNA knockdown, lentiviral transduction, and stable cell line generation for target validation. Strong bioinformatics foundation utilizing Python, R, and Bash for in silico screening, structural modeling, and therapeutic antibody development. Proven ability to bridge wet lab experimentation with computational analysis to accelerate preclinical research and drug candidate selection. Experienced in executing ELISA, MSD, ELISpot, cytotoxicity, viability, and apoptosis assays for oncology and infectious disease studies. Collaborative team contributor, supporting cross-functional workflows, training junior scientists, and implementing reproducible SOPs for assay development and molecular workflows. Advanced scientific communication skills for presenting complex datasets and assay development outcomes to technical and non-technical stakeholders. With a foundation in molecular life sciences and a track record of advancing preclinical programs, I integrate cutting-edge laboratory techniques with computational analysis to deliver data-driven insights that inform drug discovery and development strategies. Passionate about developing innovative therapeutic solutions and enhancing translational research through precision assays and bioinformatics integration.
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