Mario Alfiero

Background

About Mario Alfiero

As Director, Site Management & Monitoring (SMM), I deliver measurable results in clinical trial operations by shaping high-performing teams, driving process excellence, and fostering a culture of continuous improvement.With extensive experience leading Clinical Research Associates and Project Managers, I ensure complex studies are delivered on time, within budget, and fully compliant with ICH-GCP, local regulatory requirements, and AZ SOPs. My leadership style combines mentorship, resource optimization, and stakeholder engagement to consistently exceed recruitment targets and quality benchmarks.I am passionate about transforming clinical research operations, from feasibility assessment and start-up to monitoring and closeout. Throughout my career, I have empowered teams through effective onboarding, targeted training, and ongoing coaching—accelerating professional growth and maximizing productivity.Key strengths include strategic project planning, stakeholder management, and optimizing site performance. I thrive on developing and implementing process improvements that not only raise efficiency but also strengthen regulatory compliance and audit readiness.Whether supporting large-scale multicenter studies or advancing innovative approaches in clinical development, I am committed to delivering tangible results and elevating standards across the research landscape.