Mathieu Rouppert

Background

About Mathieu Rouppert

Passionate about innovation in healthcare, I am the founder and CEO of Substances Actives, a digital agency dedicated to supporting healthcare professionals since 2010. My goal: to help practitioners build a patient relationship that is modern, educational, and human-centered, through innovative digital tools (Visual Activ, Activ Review, Matisse) and tailored digital strategies. With my team, we design customized solutions: visual identity creation, compliant websites, educational content, online reputation management, communication automation, and artificial intelligence. Our belief: an informed patient is an empowered patient. Alongside this, I am actively involved in entrepreneurial and purpose-driven communities: • Member and Board Member of EO Paris (Entrepreneurs’ Organization), where I chair the Marketing & Communication Committee. • Regional representative for Île-de-France and board member of Amphitéa, a leading French association of health and life insurance policyholders. • Partner at Time for the Planet, an initiative dedicated to fighting climate change by creating impact-driven companies. My journey — from industrial maintenance at PSA to marketing leadership in healthcare — has shaped a hands-on, pragmatic, and results-oriented approach. Progress in healthcare isn’t just about innovating — it’s about using technology to foster relationships that are more human, more transparent, and more meaningful.