Nathaniel Wiest

Background

About Nathaniel Wiest

QUALIFICATION HIGHLIGHTS: • Clinician investigator hematology and medical oncology fellow with experience in basic and translational research, complex patient care, quality improvement, mentorship, community outreach, and advocacy. • Translational researcher specializing in the development of novel therapeutic strategies to enhance cancer treatment efficacy and tolerability. • Ongoing projects include the development of targeted nanoparticle therapeutics, the identification of synergistic therapeutic combinations, and the exploration of the incidence and implications of DNA repair gene mutations in human cancers. • Experienced with 2D, 3D, and patient-derived xenograft (PDX) models to test treatment efficacy and toxicity. • Skilled in leading cross-functional teams and liaising with clinicians, researchers, and other key collaborators. SUMMARY: • 3rd year hematology and medical oncology fellow on the CI tract at Mayo Clinic in Jacksonville. • Working to advance new combination therapies and targeted delivery systems. • Optimistic for a future of personalized and tolerable therapeutic strategies that enhance quantity and quality of time for our patients. KEY COMPETENCIES: Hematology/Oncology • Clinical Care • Patient Safety • Clinical Research • Translational Medicine Combination Therapy • Tumor Suppressors • Tumor Microenvironment • Experimental Design Chou-Talalay • Bliss Synergy • • Data Analysis • GraphPad PRISM • Calcusyn SynergyFinde • AI Models • Targeted Nanoparticles • Cell Surface Antigens Patient Derived Xenograft (PDX) Models • In Vitro/In Silico Studies • DNA Repair Deficiencies 2D/3D Spheroids • Cellcyte Gen 2 Robotic Microscope • RNA/DNA Sequencing Data Analysis Patient Care Plans • Breast Cancer • Gynecological Cancer • Genitourinary Cancer • Prostate Cancer Quality Improvement • Grant Writing • Manuscript Writing