Nicholas Lamson

Background

About Nicholas Lamson

My name is Nick Lamson, and I am a researcher with over ten years of drug delivery experience, primarily specializing in leveraging bio-inspired strategies to develop targeted drug carriers. Previously, I was a PhD candidate in the lab of Dr. Kathryn Whitehead in the Department of Chemical Engineering at CMU. My overall focus was on manipulating intestinal permeability for therapeutic purposes. Within this frame, I am interested both in increasing epithelial permeability for improved protein drug delivery, and in decreasing permeability to treat inflammatory bowel diseases. During this time, I also collaborated on projects characterizing efflux transporter inhibition as a strategy for oral small molecule delivery, as well as the importance of surface ionization at endosomal pH for lipid nanoparticles to potently deliver mRNA in vivo. I additionally built upon this experience as a postdoctoral researcher in the lab of Dr. Paula Hammond at the Koch Institute for Integrative Cancer Research at MIT. My work focused on the development of layer-by-layer electrostatically assembled polymeric nanoparticles that cross the blood brain barrier and deliver therapeutics - including small molecules, nucleic acids, and proteins - into the brain parenchyma and glioblastoma tumors.