Paul Span
Principal Investigator Radioresistance at Radboudumc
Based in Arnhem, Netherlands
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Seniority
Director
Department
Other
Location
Arnhem
Industry
Hospitals and Health Care
Company size
9.8K
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p•••••••@radboudumc.nl
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Background
About Paul Span
My group at the Radiotherapy & OncoImmunology (ROI) laboratory (dept. Radiation Oncology, Radboudumc, Nijmegen), focusses on mechanisms of insensitivity to radiotherapy (radioresistance), combining preclinical research with clinical validation in various cancer patient cohorts. The radiobiological projects I supervise explore a range of potential causes of radioresistance, from the tumor (micro)environment (hypoxia, autophagy, metabolism), genomic instability (APOBEC), to off-target effects of endocrine treatment (tamoxifen). I have been chair of the PathoBiology Group (PBG) of the European Organisation for Research and Treatment of Cancer (EORTC), and of the Women’s Cancers research theme of the Radboudumc. Currently, I am chair of the internal KWF/ROF committee, member of the Scientific Advisory Group Radiobiology 2023/2025 and Biology committee of the European SocieTy of Radiation Oncology (ESTRO), and board member of the Dutch Society of Radiobiology (NVRB).
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