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Pierre Lutz

Directeur De Recherche Cnrs, Institut Toulousain Des Maladies Infectieuses Et Inflammatoires at Inserm

Based in France

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Seniority

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Location

France

Industry

Research Services

Company size

7.7K

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Email

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p•••••••@inserm.fr

Phone

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+33 ••• •••• ••••

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Background

About Pierre Lutz

Enzymes d’ubiquitylation dans la réponse immunitaire en conditions saines et pathologiques: Notre compréhension des mécanismes biologiques impliquant l’ubiquitine a largement progressé au cours de la dernière décennie et il est maintenant établi que la conjugaison de l’ubiquitine à des protéines cibles régule de nombreuse activités biologiques. Notre objectif général est de mieux comprendre les mécanismes contrôlant l’ubiquitylation et la déubiquitylation des protéines dans la réponse immunitaire en conditions physiologiques et pathologiques afin d’identifier de nouveaux biomarqueurs et de nouvelles cibles thérapeutiques d’intérêt pour la médecine de précision. Ubiquitin Enzymes in Immunity & Disease: Insight into the world of ubiquitin has expanded considerably over the past decade and ubiquitin conjugation to proteins is known to be involved in controlling major biological processes. Our main goal is to better understand ubiquitylation/deubiquitylation events in immunity and disease to identify novel biomarkers and therapeutic targets for precision medicine.

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