Renan Sper
Principal Scientist at Mammoth Biosciences
Based in San Francisco, United States
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Seniority
Director
Department
Science
Location
San Francisco
Industry
Biotechnology Research
Company size
164
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r•••••••@mammoth.bio
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Background
About Renan Sper
About Me: I am a passionate and innovative Principal Scientist and Preclinical Development Leader with over 15 years of experience spanning academia and the biotech industry. My expertise lies in gene editing and gene therapy for neuromuscular diseases, where I have successfully advanced novel genetic therapies from discovery through preclinical development. My work integrates CRISPR-based screening, muscle-targeted gene delivery, and translational bioanalytical methods, bridging scientific discovery with real-world therapeutic applications. With a Ph.D. in Comparative Biomedical Science & Cell Biology and postdoctoral training in Maternal-Fetal Precision Medicine at UCSF, I bring a deep understanding of developmental biology, molecular genetics, and regenerative medicine. My research background includes pioneering work in in utero fetal stem cell and molecular therapies, CRISPR-Cas9 transgenic models, and nanoparticle-mediated gene delivery, driving innovative approaches to treating genetic disorders. I initially trained as a Veterinarian, providing me with a unique clinical perspective that informs my approach to translational research and therapeutic development. This diverse expertise enables me to design and execute preclinical studies with a strong understanding of clinical applications, ensuring that research advancements are aligned with patient needs. Beyond technical expertise, I am deeply committed to mentoring and leading scientific teams, fostering collaboration, and translating complex research insights into actionable strategies for diverse stakeholders. I thrive in fast-paced, high-impact environments, where I can contribute to groundbreaking discoveries and shape the future of genetic medicine. Areas of Expertise: Gene Editing & CRISPR-Based Screening Viral and non-Viral & Muscle-Targeted Gene Delivery Neuromuscular Disease Therapeutics Preclinical Study Design & Execution Translational Bioanalytical Methods Stem Cell & Molecular Therapies Scientific Leadership & Cross-Functional Collaboration I am always eager to connect with fellow scientists, biotech leaders, and industry professionals to collaborate on advancing transformative therapies that push the boundaries of medicine. If you're interested in discussing research, collaboration opportunities, or simply exchanging insights, feel free to reach out!
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