Sameera Senaweera
Senior Scientist Ii at Abbvie
Based in Lake Bluff, United States
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Seniority
Staff
Department
Science
Location
Lake Bluff
Industry
Pharmaceutical Manufacturing
Company size
61K
Contact information
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s•••••••@abbvie.com
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Background
About Sameera Senaweera
An accomplished PhD chemist with 8+ years of cumulative experience in synthetic organic chemistry and medicinal chemistry. Developed unprecedented photocatalytic C-F functionalization chemistry from the ground up. Partnered with leading chemical companies (Sigma and Aspira) to commercialize self-developed synthetic products. Executed syntheses from mg to ~100 g scale. Experienced in flow chemistry and multi-step syntheses. Proficient in NMR, HPLC, GCMS, LCMS, FTIR, microwave reactors, and automated column chromatography. Developed potent chemotypes for a cancer (TDP2) and multiple viral targets (HBV, HCMV, and SARS CoV-2). Synthesized potent, modified nucleoside compounds, photoaffinity probes, and covalent probes. Proficient in molecular modeling (Schrödinger and PyMOL), pharmacophore modeling, ligand/structure based drug design, virtual screening, and hit optimization. A project manager with mentoring experience.
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