Stephen Edwards

Background

About Stephen Edwards

Stephen Edwards has more than 20 years of experience in pharmacology and toxicology across academia, government, and industry. He has experience with data mining, design of web-accessible knowledgebases, ontology-based modeling of biological information, biomarker definition and applications, microarray analysis, sequence analysis, database design, and statistical computing. Prior to joining RTI International, Dr. Edwards was a systems biologist at the U.S. Environmental Protection Agency (EPA). In this role, he used computational approaches to describe the mechanisms by which chemicals cause disease in a wide variety of species. This work served as the basis for interpretation of high-throughput toxicity test results allowing thousands of chemicals per week to be screened for toxicity potential. Before joining EPA, Dr. Edwards worked in the pharmaceutical industry where he led a target discovery team focused on novel diabetes targets. The team used biological networks built from genetics and gene expression data to identify potential diabetes targets, which were subsequently nominated for the Merck high throughput screening program. Dr. Edwards has more than 50 peer-reviewed publications and was the chief architect of the Adverse Outcome Pathway Wiki (https://aopwiki.org/).