Sun Hyung Kwon

Background

About Sun Hyung Kwon

Highly-motivated biomedical researcher with expertise in pharmacology, organ fibrosis, biomarker discovery, regenerative medicine, stem cell biology, toxicology & drug delivery- Extensive knowledge in localized drug delivery in rodent and porcine disease models (direct experience in vascular stenosis (AV graft/fistula), skin/liver/lung fibrosis, diabetic ulcers & hypertrophic wound healing, foreign body immunology, osteoarthritis & parabiosis models)- Hands-on experience in clinical biomarker research, pre-clinical efficacy, IND-enabling PK/PD studies. Experience preparing for FDA pre-IND/IND documents & ODD applications- Direct experience in designing First-in-Human and Phase I trials for topical small molecule drug delivery- Developed and demonstrated pre-clinical efficacy/safety of a bioscaffold-based small molecule kinase inhibitor delivery platform for topical/transdermal applications in anti-fibrosis scar therapy- Developed ex vivo vascular culture system for anti-neoplastic drug candidate screening- Demonstrated pre-clinical efficacy of a small molecule anti-cancer drug delivered via peri-vascular system for hemodialysis vascular access stenosis- Trained in regulatory sciences (early drug development, non-clinical safety assessment & FDA pre-IND/IND filing) and clinical research and drug development- Skilled in molecular biology & biochemistry techniques including multiplex assays, RT-PCR, microarray, Luminex, histopathology, immunoassays, fluorescent & multi-photon microscopy, IVIS imaging, flow cytometry, 3D & ex vivo organ culture- Strong communication skills, excellent grant writer & passionate for innovative drug therapy research- Filed 3 US patents (pending) and published 20 original papers in Science, Nature Communications, Science Translational Medicine, and other highly recognized physiology & pharmacology journals.