Tamas Lukacsovich

Background

About Tamas Lukacsovich

In the course of my career I changed my working subject from immunology to bacterial transcriptional regulation to studying homologous recombination in mammalian tissue culture and then to Drosophila behavioral genetics and lately transgenic mouse models. During these switches I acquired comprehensive knowledge about different scientific fields but connected these distant areas by applying the same innovative molecular biological tools. While discovering the secrets of Mother Nature and analyzing its complex processes or features is highly rewarding, I find it immensely satisfying to design precious new “work of art”s. Due to this predisposition I have been part of many collaborations, both locally and internationally. In most of the projects I have been involved in designing and creating the biological system, which then provided the basis of the ensuing research. One of this work was the Dual-Tagged Gene-Trap vector, which is now the integrant part of the Berkeley Drosophila Genome Project. My more recent works included, among other projects, a lentivirus vector systems for in vivo neuronal tissue recovery experiments for potential treatment of brain injuries, an artificial selfish gene drive vector which could promote the proliferation of any joint marker in an entire insect population and CRISPR based floxing constructs for generating transgenic mouse models with inducible expression or elimination of the targeted gene. Currently I am also pursuing the accomplishment of an experimental plan to identify small molecule mimics of bioactive peptides. Proof of principle experiments verified the feasibility of the idea, which could become a breakthrough in the development of new antibiotics and anti-cancer drugs.