Vladimir Khayenko
Gmp Chemist, Medicinal Chemistry at Abx Advanced Biochemical Compounds Gmbh
Based in Dresden, Germany
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Seniority
Staff
Department
Science
Location
Dresden
Industry
Pharmaceutical Manufacturing
Company size
156
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Background
About Vladimir Khayenko
WORK EXPERIENCE Since June 2018 - December 2022 Julius-Maximilians-University of Wuerzburg, Rudolf Virchow Center. Research Scientist Developed and applied “Sylites” synthetic activity-related probes for the visualization of inhibitory synapses and brain circuit mapping. Developed novel peptidic probes for the inhibition of Hepatitis B virion formation. Explored protein-protein interaction modulation in a microarray format. Participated in grant writing for the (granted) Emmy Noether Program. Supervised Bachelor and Master Biology, Biomedicine and Biochemistry students. Trained laboratory personnel for routine techniques. 10.2013-10.2017 The Hebrew University of Jerusalem, Israel. Research Assistant and Research Scientist Developed a peptide-based probe targeting M2 macrophages. Grant - Israel Ministry of Trade and Industry Kamin-Yeda Program. EDUCATION 06.2018-07.2022 (expected) PhD Biomedicine. Julius-Maximilians-University of Wuerzburg, Germany. Title: “Synthetic probes for microscopy and pharmacological applications”. 10.2015-11.2017 M.Sc. Pharmacy – Medicinal Chemistry (magna cum laude). GPA 94.99/100. The Hebrew University of Jerusalem, Israel. Title: “Targeted Cathepsin inhibition in M2 macrophages”. 10.2011-10.2015 B.Sc. Pharmacy (magna cum laude). GPA 89.38/100. The Hebrew University of Jerusalem, Israel. ADDITIONAL QUALIFICATIONS 2019 Oral presentation. 2018 Intercultural communication; Good scientific practice. 2017 Biomedical industry (IP, Technology transfer, GMP, R&D); Interpersonal communication. 2016 Pharmaceutical industry (GMP, SOP's, regulatory affairs); Statistics; Peptides and Oligonucleotides. TECHNICAL SKILLS Chemistry Peptide and peptidomimetics synthesis - from hand synthesis to high throughput large-scale automated synthesis; fluorophore conjugations; click chemistry; general organic chemistry; HPLC analytical and preparative; LC-MS. Biology Cell cultures; immunocyto- and histochemistry; SDS-PAGE and western blots; peptide microarrays; isothermal titration calorimetry; bioconjugation and protein purification; ELISA; animal work. Microscopy Wide-field and confocal microscopy; single-molecule localization microscopy (dSTORM); scientific image processing and analysis. COMPUTER SKILLS MS Office, Mendeley, Endnote, Graphpad Prism, Inkscape (Adobe Illustrator equivalent). Chemdraw, Shimadzu LabSolutions, Agilent OpenLab, Thermo Fisher Chromeleon & Xcalibur. ImageJ, basic Python and Java programming, automated image processing and analysis.
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