Xavier Lucas
Associate Director at Monte Rosa Therapeutics
Based in Basel, Switzerland
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Seniority
Manager
Department
Research & Development
Location
Basel
Industry
Biotechnology Research
Company size
227
Contact information
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x•••••••@monterosatx.com
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Background
About Xavier Lucas
Digital medicinal chemist with a focus on structure-based approaches. I'm gaining industry experience in supporting drug design projects covering different therapeutic areas and modalities, spanning from early target assessment up to LI/LO. I apply molecular modelling, core hopping, library enumeration, molecular dynamics, FEP calculations, machine learning, quantum mechanics, and QM/ML methods, among others, where appropriate. I am a co-author of several patents arising from my industry work.Currently, and beyond portfolio project work, I am involved in the implementation of ADME ML models and in the expansion of the molecular glue degrader compound library at Monte Rosa Therapeutics.During my postdoc, I was awarded a Marie-Curie Fellowship to carry out research in targeted protein degradation, and as a team, we presented the first X-ray crystal structure of a PROTAC in ternary complex with an E3 ligase and a target protein.
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