Yubin Li

Background

About Yubin Li

Ph.D. in Pharmaceutical Chemistry with 10+ years’ academic and industrial research experience in developing targeted autoimmune/inflammatory and tumor therapeutics; translational research experience in dermatomyositis, cutaneous lupus, and lupus nephritis; research experience in gene therapy for renal diseases and acute hepatitis; research experience in evaluating toxicity of drug-delivery polymeric nanomaterials;·Design and implement critical studies required to drive hypothesis-driven research, efficient at acquiring and analyzing research data, proficient in writing scientific reports and maintaining research lab operations and equipment;· Effective communication, collaboration skills and project management experience: Led one VA Grant as co-PI, led one industry-funded translational project, and granted two patents as co-inventors;·Knowledgeable in monocyte/macrophage and neutrophil biology with solid skills in isolation and differentiation of human/mouse macrophage and neutrophils; hands-on experience in T cells activation, differentiation, and polarization; skin related keratinocyte, fibroblast isolation and sebocyte culture;·Excellent assay development skills, including molecular biology, molecular cloning, protein expression and purification, primary cell isolation, cell culture, cell proliferation, cell differentiation, cytotoxicity, cell death, transfection, siRNA, ELISA (MSD), RT-PCR, immunoblot, immunoprecipitation, immunoassays, mixed lymphocyte reaction (MLR), luminex multiplex assay, reactive oxygen species (ROS) assay, extracellular traps and extracellular vesicles assay, flow cytometry, immunohistochemistry, immunofluorescent staining, fluorescence microscopy, RNA and DNA isolation, tissue collection, and laser capture microdissection;·Strong working knowledge of preclinical animal models and in vivo study design, including skin inflammation models, renal disease (diabetic nephropathy) mouse model, autoimmune hepatitis mouse models, and mouse handling (drug dosing by i.v, i.p, s.c, blood draws, breeding, genotyping, and bone marrow transplant);·Proven scientific accomplishments evidences by first author/corresponding author publications in high impact journals (including Theranostics, Biomaterials, Autophagy) and books, and presented original scientific research in national and international conferences.