Zi Fan
Principal Scientist at Nuvalent, Inc
Based in United States
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Seniority
Director
Department
Science
Location
United States
Industry
Biotechnology Research
Company size
308
Contact information
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z•••••••@nuvalent.com
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Background
About Zi Fan
Accomplished data science leader with 10+ years of experience in oncology drug discovery, leveraging integrative genomics, real-world patient data, and AI/ML to drive biomarker strategy, patient stratification, translational research• Deep expertise in cancer biology, immuno-oncology, and cell therapy, with strong technical proficiency in statistical programming, omics analytics, AI/LLM-powered PubMed literature text-mining• Recently transitioned into a translational leadership role, driving patient selection strategy, biomarker development, and clinical protocol authorship for a pan-mutant-selective PIK3CA inhibitor (ETX-636), integrating genomics, literature insights, and real-world clinical data to inform early clinical development• Highly collaborative and cross-functional, partnering with wet-lab scientists and clinical teams to design experimental and clinical studies, analyze multi-omic datasets, and generate data-driven insights to guide pipeline decisions• Proven scientific leadership and people manager, building high-performing teams and advancing therapeutic innovation through internal excellence and external collaboration with academic and industry partners
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