Zinaida Good

Background

About Zinaida Good

I am an Assistant Professor of Medicine in the Division of Immunology and Rheumatology and the Center for Biomedical Informatics Research at the Stanford University School of Medicine and the Director of the Cancer Cell Therapy Data Hub at the Stanford Center for Cancer Cell Therapy. My research program focuses on understanding and enhancing engineered T cell immunotherapies for cancer and immune-mediated diseases through innovative computational approaches and systems immunology. During my postdoctoral training with Drs. Crystal Mackall and Sylvia Plevritis, I performed fate mapping studies to identify features of optimal CAR T cells in large B cell lymphoma (LBCL) and diffuse midline glioma (DMG), and discovered the role of CAR T regulatory cells in resistance to CD19-CAR in LBCL. I completed my Ph.D. studies in Computational & Systems Immunology at Stanford University, where I trained with Drs. Garry Nolan and Sean Bendall and developed methods to build and leverage lymphocyte differentiation trajectories in health and cancer. My background in experimental immunology and oncology combines two years of experience in Discovery Oncology at Genentech with B.S. and M.S. degrees in Microbiology & Immunology from the University of British Columbia, where I investigated mechanisms of T cell memory with Dr. Michael Gold. My work includes 4 first-author papers (Nature Medicine 2018 & 2022, Nature Biotechnology 2019, Trends in Immunology 2019), 17 co-authored papers (including Nature 2019, 2022, 2024, Science 2021, Nature Methods 2016, 2022, and NEJM 2024), and 2 patent applications. My research is supported by the NIH Pathway to Independence Award, Parker Bridge Fellowship, American Cancer Society Institutional Research Grant, and Parker Innovation Challenge Grant. I have been named an Arthur & Sandra Irving Cancer Immunology Fellow in 2022 and an AACR-Woman in Cancer Research Scholar in 2024. I am deeply committed to training and supporting the next generation of scientists who will drive innovation in biomedical research. My lab provides a collaborative, intellectually stimulating environment where trainees can develop the technical skills, critical thinking abilities, and professional competencies needed for successful careers in science. In the Good Lab, we integrate cutting-edge synthetic biology, immunology, and machine learning to engineer next-generation T cell therapies for cancer and autoimmune diseases: Lab website: X: https://x.com/GoodZinaida Bluesky:@zinagood.bsky.social