Beonchip

Beonchip offers disposable systems to recreate in-vitro biological enviroments using microtechnologies Our different products are easy to handle for researchers not initiated in microfluidic. BE-Flow: is our most easy-to-use device dedicated to cell culture under flow. It allows the performance of long term 2D or 3D culture in two independent channels. BE-Flow is compatible with any microfluidic pump system and can be used simply with a rocker, thanks to its fluid reservoirs situated by the inlets/outlets. This is an optimal device for vascular research where shear stress plays a major role in gene expression. BE-Gradient: is our device designed for the application of electrochemical gradients to 3D cell cultures. BE-Gradient is compatible with any type of optical microscopy (inverted phase contrast, confocal, fluorescence.). Be-Gradient consists of a central chamber for cell culture and two lateral channels connecting to the central chamber through 5 small microchannels. 2D culture is also possible for adherent cells not only in the central chamber but also in the lateral channels. BE-Transflow is our most versatile cell culture platform. It allows the study of complex culture configurations by joining a culture well with a microfluidic channel via a porous membrane. This is the optimal device for Air Liquid Interface (ALI) culture, endothelium/epithelium barrier and crosstalk studies. BE-Doubleflow: is our most advanced device. It consists of two perfusable channels connected via a porous membrane. Explore the crosstalk between different 2D and 3D cultures in a biomimetic environment and control the efficiency of the interaction by selecting the optimal pore size for your application. This is the optimal device when a hypoxia environment is needed, for studying the effect of circulating particles (bacteria, immune system, circulating tumor cells) and for endothelium/epithelium barrier when no ALI is needed or when flux plays a role in both sides of the coculture