Vesiculab

Vesiculab provides innovative and efficient solutions for nano-bio research. This includes extracellular vesicles (EVs), gene therapy and nano-medicines. Based in Nottingham, UK, the company aims to support scientists worldwide with reagents and consumables that facilitate pre- and post-analytics sample preparation. Vesiculab develops products enabling translational research at the nanoscale, more specifically to the study of the following entities: • Extracellular vesicles (exosomes, microvesicles) • Nanomedicines (lipid nanoparticles, liposomes) • Viral vectors (lentivirus, adeno-associated virus) • Other bio or synthetic nanoparticle (virus, vaccines, virus-like particles) Current product line-up include: Vesi-Ref CD63-GFP: an extracellular vesicle reference material that enables the correct assessment of size and concentration measurement parameters with the most commonly used analytical techniques. Because the EVs that constitute this product express GFP in the presence of CD63, it can also be used to calibrate fluorescence detection sensitivity in flow cytometry, fluorescent nanoparticle tracking (f-NTA) and other techniques capable of fluorescence detection. Vesi-ref CD63 GFP is compatible with: • Nanoparticle tracking analysis (NTA) • (nano) flow cytometry • Dynamic light scattering (DLS) • Single-particle interferometric reflectance imaging sensor (SP-IRIS) • Resistive pulse sensing Vesi-Dye LMB-600: a fluorescent probe specific to lipid bi-layers, which is used as a universal label for extracellular vesicles, liposomes, LNPs, lentiviruses and gram-positive bacteria. Because of its excitation range between 488-525nm and a maximum emission wavelength at 600nm it offers great flexibility and performance. Vesi-Dye LMB-600 is compatible with: • (nano) flow cytometry • Fluorescence nanoparticle tracking analysis (F-NTA) • Fluorescence microfluidic resistive pulse sensing (F-MRPS) • Confocal microscopy