Cara Fraley

Background

About Cara Fraley

Biotechnology professional with extensive experience from early discovery through pre-clinical development with a focus in protein science, protein production, assay development and CRO management. Proven success in R&D project management for multi-faceted projects with tight deadlines, leveraging both internal and external resources. Drug Discovery | Scientist | Protein Sciences | Assay Development | CRO Management | ex-Broad Institute | ex-Biogen Core Competencies: Research and Program Leadership: o Strategic prioritization of multiple projects, including timeline and resource management o Strong communication and collaboration among diverse stakeholders o CRO identification, legal contract coordination and relationship management o Anticipate resolutions for current and forecasted issues o Management of diverse R&D deliverables for tight project deadlines o Mentorship of junior scientists o PMP Certification expected Spring 2025 Technical Expertise: o Protein Sciences: recombinant protein design/engineering, computational biology collaborations, protein purification and characterization, protein refolding, protein-protein binding interactions, protein complexes, Tag-Catcher ligation system, bacterial, insect/baculovirus and mammalian expression systems, scaled up production, co-expression with chaperones, CRO management o Molecular Biology: variety of cloning strategies (restriction digest, Golden Gate, Gibson assembly, multicistronic vector, bacmid preparation) o Biochemistry: BLI (binding study, small molecule screening), ELISA (pre-clinical PK, competition), AlphaLISA, DSF, qPCR, DEL Screens o Cell Biology: Stable cell line development, cell-based assays Always open to conversations carafraley@mac.com