Chetan Nehate

Background

About Chetan Nehate

I, Nehate Chetan Narayan, a biomedical engineer. My area of focus is formulation and development and applying Quality-by-Design (QbD) in product designing process for development of novel drug delivery systems in ophthalmic and parenteral for the US market. I am well-versed in pharmaceutical product development pipeline to work independently or as well as part of a team in industrial settings or academics. I have appreciable scientific expertise in following fields, • Polymer Synthesis, Bioconjugation techniques • Formulation Development • Well versed in use of- Analytical instruments and techniques like HPLC, GPC, FTIR, NMR, DSC, UV-visible spectroscopy, fluorescence spectroscopy, optical and polarized light microscopy, hot and cold stage microscopy, circular dichroism, Malvern zeta sizer, homogenizer, probe sonicator, bench top lyophilizer, gel electrophoresis. Processing equipments like high pressure homogenizer, spray drier, air jet mill and fluid bed dryer. Cell culture techniques like confocal microscopy, flow cytometry and fluorescence microscopy, RT-PCR. Solubility and dissolution studies Stability studies as per ICH guidelines • Solid state characterization (molecular, particle and bulk level properties) Concept of crystallinity, polymorphism, hydrates, solvates, desolvates and amorphous state Solid state stability • Appreciable understanding of the data interpretation of FTIR, 1H-NMR, 13C-NMR, GPC, SEM, TEM, AFM, EDX, XPS, FACS, circular dichroism, CHNS, DSC, TGA etc. • Appreciable understanding of the concepts related to Intellectual Property Rights (IPRs) and drug regulatory affairs. • Well versed with softwares like empower 3, Breeze 3, ChemDraw, ACD ChemSketch, Origin, CasaXPS, SigmaStat, Graph Pad Prism 7, Flowing software, Endnote, Mendeley and Microsoft office. • Experience in handling mice with various routes of administration like oral, intravenous, intraperitoneal, intratumoral and subcutaneous.